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What is MGUS?

A cluster of red blood cells

You might already know that multiple myeloma is more common among African Americans, but why? The answer might have something to do with a condition called MGUS.

MGUS (pronounced “em guss”) is short for monoclonal gammopathy of undetermined significance. Now, that’s a mouthful, so most doctors just say MGUS for short.

MGUS is a condition in which an abnormal protein (called monoclonal protein or M-protein) is in your blood.

MGUS isn’t cancer and it’s not a dangerous condition, but it can progress to active multiple myeloma. African Americans are more likely to develop MGUS and do so at a younger age.

This could be part of the reason why myeloma is so much more common in the African-American community.

Related information

Multiple Myeloma in African Americans

Find out what’s different about multiple myeloma in African Americans.

Getting Appropriate Treatment

Learn tips for getting the best possible care.

How Is Multiple Myeloma Treated?

Read about the different options that are available to treat multiple myeloma.


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